Cleaning in Place (CIP) systems for the pharmaceutical industry

In pharmaceutical processes, cleanliness and sterility are imperative requirements. C.L.A. Cleaning in Place (CIP) systems, designed on URS, ensure hygiene, traceability and validation. Integratable with plant utilities (CIP/SIP), they are constructed of Stainless steel and Special alloys and accompanied by comprehensive documentation to support industry regulations.

Applications

CIP C.L.A. systems are used for in-house and automated cleaning of pharmaceutical plants, reducing downtime and ensuring repeatability and compliance with quality standards. Each system is developed to order to fit solid, liquid, or semisolid drug production lines.

Specifications

Design on URS: developed on customer process and plant specifications
Complete structure: storage tanks, recirculation pumps, heat exchangers and automation with valves
Materials: stainless steel AISI 304, 316L, 904; Special alloys HC22, HC276, SAF
Integration: provision for connection with plant utilities (CIP/SIP)
Certifications: PED 2014/68/EU compliance; UNI EN ISO 9001 certified quality system
Documentation: IQ/OQ documentation included; FAT and SAT available upon request

Benefits for the pharmaceutical industry

GMP compliance: design, materials and documentation in line with pharmaceutical standards
Facilitated validation: IQ/OQ, FAT and SAT to support audits and quality control
Reduced downtime: automatic flushing without disassembly of equipment
Traceability: comprehensive technical documentation to support regulated processes

FAQ

Do CIP C.L.A.’s comply with GMP standards?

Yes, thanks to the design on URS, material selection and comprehensive technical documentation (IQ/OQ, FAT, SAT).

Can CIPs be integrated with site utilities?

Yes, the systems are prepared for connection to plant CIP/SIP, ensuring compatibility and business continuity.

What materials are available for pharmaceutical CIPs?

Stainless steels AISI 304, 316L, 904 and Special alloys HC22, HC276 and SAF, selected according to the customer’s URS.

What documentation accompanies the systems?

CLA provides dimensional certificates, tests, IQ/OQ and, upon request, FAT and SAT to support validation.