Preparation systems for liquids and powders in the pharmaceutical industry

Preparation systems for liquids and powders for the pharmaceutical industry designed by C.L.A. are complete, reliable solutions that comply with the strictest GMP standards. Each system is designed to batch process liquid, semisolid solutions and powder-liquid mixtures in complete safety and traceability.

Specifications

Internal finish: roughness Ra < 0.5 µm to ensure cleanability and sterility
Plant capacities: from 10 to 3000 liters
Stirring: from the top or the bottom, also with magnetic drag to reduce risk of contamination
Compatibility with CIP/SIP: can be integrated and connected directly to plant utilities
Heating: thermal jackets and/or electric heaters with temperature control
Approved pressures: 1+6 bar in body, 1+3 bar in jacket

Process control and documentation

Semi-automatic control panel for standard operations
PLC option: automated management of parameters, recipes and temperature control
Recording and printing: batch traceability
Certifications: PED 2014/68/EU compliance
Qualifications: IQ, OQ, FAT, SAT available upon request

Available components and options

Vacuum pump for injection management or air removal
Load cells for check weighing during preparation
Heating liquid recirculation and product transfer pump
Integrable sensors for temperature, pressure, conductivity, level

Typical applications for the Pharmaceutical sector

Oral preparations, syrups, lavages, skin gels
Sterile or nonsterile liquid- or gel-based solutions
Mixtures with active ingredient in powder form dissolved in solvents or liquid vehicles

FAQ

Is it suitable for use in clean rooms?

Yes, the materials, finishes and system configuration meet GMP requirements for controlled environments.

Can the system be integrated with my utilities and SCADA?

Absolutely. Plants are designed for direct connection to existing utilities and plant automation.

Can I obtain documentation for validation?

Yes, C.L.A. provides all necessary documentation: IQ, OQ, FAT, SAT, PED, material and welding certificates.

Is it possible to manage multiple recipes on one plant?

Yes, with PLC integration you can manage recipes, parameters and batch records in an automated way.